AB0383 CARDIAC INVOLVEMENT IN RHEUMATOID ARTHRITIS: A COMPARATIVE TRANSTHORACIC ECHOCARDIOGRAPHY STUDY

Background Cardiac involvement in rheumatoid arthritis (RA) is one of the most frequent and severe extra-articular manifestations, but it often under-diagnosed. Objectives In this context, we conducted study, whose objective to determine prevalence types cardiac abnormalities patients with RA using transthoracic echocardiography (TTE) compare them control subjects. Methods We performed a comparative cross-sectional study Taher Sfar Hospital, Mahdia, Tunisia. Each patient underwent TTE coupled Strain technique. Results Seventy-two according ACR/EULAR 2010 criteria 72 subjects (control group) were included. our there was clear female predominance both groups sex ratio 0.07 group 0.05 (p=1). The mean age 52.9 ± 11.72 years [21-75 years] that 49.26 10.74 [19-76 (p=0,06). Abnormalities detected by more compared (80.6% vs 36.1%; p < 0.01) they asymptomatic 65.5% cases group. Pericardial effusion without significant difference. Valvular significantly (45.8% 1.4%; p<0.01) tricuspid (31.9%). Left ventricular diastolic dysfunction difference (36.1% 13.9%; p<0.01). Regarding left systolic dysfunction, ejection fraction impairment absent groups, subclinical myocardial damage assessed Global Longitudinal (GLS) method 37.5% 16.6% (p<0.01). GLS -17.8% 2.9 [-22 -10.7%], while -19.4% 1.9 [-24.7 -15.7%] hypertrophy on 22.2% 6.9% Pulmonary arterial hypertension present only (2.8% cases). Conclusion Our showed than general population, hence interest systematic screening, order improve quality life vital prognosis patients. References [1]Shenavar Masooleh I, Zayeni H, Haji-Abbasi A, Azarpira M, Hadian Hassankhani et al. arthritis: A Iran. Indian Heart J 2016;68:332–5. [2]Guedes C, Bianchi-Fior P, Cormier B, Barthelemy Rat AC, Boissier MC. manifestations case-control transesophageal 30 Arthritis Care Res 2001;45:129–35. Acknowledgements: NIL. Disclosure Interests None Declared.